Feline Immunodeficiency Virus (FIV)

Feline Immunodeficiency Virus (FIV) belongs to the family of retrovirus in a group called lentiviruses (these are capable of lying dormant and cause disease slowly). It is also known as Feline AIDS. FIV is species specific – which means other pets, animals and humans cannot get infected when exposed to the disease causing agents.

The virus cannot survive in the environment for long and can be killed easily by common disinfectants.

The primary mode of transmission is by direct contact with infected saliva. Cat bites, grooming (involving saliva) between cats, blood transfusions, from a pregnant mother to her kittens.

Outdoor cats are at a high risk as compared to indoor cats as they have a greater risk of exposure. Once a cat has been infected with FIV, it will remain infected with the virus for life (the infection is permanent). A cats body becomes incapable of developing a normal immunity response. Though infected, a cat will remain healthy for years. Gradually, as the effect of virus progresses, the immune system is completely destroyed. FIV infects the cells of the immune system (white blood cells [WBC]) mainly lymphocytes. The virus damages or kills the cells or may alter their normal function.

During the first few weeks of infection, the cats defenses do build up, but are unable to completely ward of the virus. FIV keeps multiplying at a very slow level. Clinical signs as so mild that it may go unnoticed. The first diagnosis happens between 3 to 5 years post getting infected.

FIV is a slow progressing disease and a cat will not show any symptoms of being infected. A declined and weakened immunity makes the cat susceptible to other secondary infections and diseases.


FIV is caused by retrovirus. It can be spread only in a few circumstances such as cat bites from infected cat, wounds, pregnant queens to her kittens, mutual grooming and in rare cases infected blood transfusions.

Clinical Signs & Symptoms

FIV causes disease through immunosuppression (weakened immunity system which is susceptible to secondary infections) and may not show the symptoms for years. The normal immune functions of the cat are altered, the cat is prone to other diseases and infections. There are no specific signs with this infection.

Some of the signs to watch for are:
› Lethargy
› Pyrexia (Fever)
› Anorexia (Loss of Appetite)
› Alopecia (Hair Loss)
› Diarrhea (Loose stools)
› Pollakiuria (Frequent urination)
› Anemia
› lymphadenitis (swelling of lymph nodes)
› Weight loss
› Gingivitis (Inflammation of the gums)
› Stomatitis (Inflammation of the mouth)
› Skin diseases
› Recurrent ocular discharges
› Recurrent nasal discharges
› Gastrointestinal tract diseases
› Respiratory diseases
› Uveitis (inflammation of the inner pigmented structure of the eye)
› Conjunctivitis (Inflammation of the eye)
› Haemoplasma infections
› Lymphoma
› Central nervous system (CNS) signs
› Toxoplasmosis

(Note: minor infections will keep occurring over time and they will take a longer time to heal. Wounds will take longer than usual to heal)


Diagnostic tests are performed to to detect the presence of FIV and rule out other diseases which can cause similar symptoms. FIV can be easily confused with Feline Leukemia Virus (FeLV) as they both cause similar secondary infections.

Veterinarians will require a complete history of your cat which includes medical history, vaccination records, existing health concerns, current and previous medications, onset of symptoms, diet and exercise routine and any information which can help in establishing a correct diagnosis. Diagnosis is done with a combination of tests. These include routine lab examinations and special tests which can detect the presence of the virus. They are:

› Physical examination
› Complete Blood Count (CBC) conducted for platelet count and signs of any inflammation and anemia
› Biochemical profile – this checks for antibodies, if the result is positive, which means the cat has FIV
› ELISA test (Enzyme-Linked Immunosorbent Assay)
› PCR test (Polymerase Chain Reaction)


There is no cure for FIV. FIV infected cats can live for a long period of time (upto five years from the time they are infected). The treatments associated with FIV are to prevent further spread of the disease to other cats and because a cats immune response is compromised, it is prone to secondary infections which may cause health issues. Your veterinarian may advise you of the supportive treatments your cat should get. They are:

› Vaccination protocols
› Antibiotic medications
› Drugs to treat secondary illnesses and diseases
› Immunity enhancing medicines
› Neutering the FIV infected cat


Vaccination is the single most effective way to prevent the disease. Keep in mind FIV has a global distribution – it is present everywhere. Please consult your veterinarian and ways to prevent your cat from getting infected and talk about the vaccine schedule.

Home Care

FIV causes immunosupression. Your cat is at a higher risk of getting secondary infections.

› Vaccinating your cat. Choice is generally nasal vaccines as they work faster.

Once diagnosis confirms FIV:

› A well planned, nutritious diet is necessary in such conditions (avoid raw foods). Routine and regular checkups to access the progress, further tests may be advised.
› Do not allow your pet to roam freely. This works two ways, firstly if the pet is infected, it greatly reduces the chances of risk of exposure to other pets and humans and secondly in-case of a healthy pet, it reduces the chances of contracting the infection. Do not allow your pet to go through garbage bins, water sources, fecal infected areas.
DO NOT BREED cats diagnosed with this disease.

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